World Sickle Cell Day

By Eilene E. Guy, American Red Cross Volunteer

What do Juneteenth (today) and World Sickle Cell Day (also today) have in common? Both of these events focus on African Americans.

Glinda Dames-Fincher is a member of the American Red Cross Sickle Cell Sub-committee in northern Ohio. She’s a proud, outspoken “sickle cell warrior” calling for more Black blood donors.

Glinda Dames-Fincher

“Over 80 percent of Americans with Sickle Cell Anemia are of African descent, and ethnicity matters with blood transfusion,” she said. Many individuals who are Black have unique structures on their red blood cells that make their donations the most compatible to help patients with sickle cell disease. Glinda likes to think of it as “special sauce.”

“So please, African Americans, roll up your sleeves and help sickle cell warriors like me fight their battle!”

For Glinda, the need is personal. In order to combat the many effects of sickle cell (SCD) on her body, she gets two units of red blood cells every month; the procedure involves withdrawing one unit of her damaged blood each time and then transfusing in two units of healthy red cells.

She figures she’s received more than 600 units of red cells, between regular transfusions and the many surgeries she’s undergone to repair organs damaged by oxygen deprivation.

Glinda is a wealth of knowledge about sickle cell:

 This inherited disorder makes red blood cells sticky, rigid and curl into a C “sickle” shape, limiting their ability to carry oxygen into every tissue in the body. The misshapen cells also tend to clump, leading to various complications. “For many pediatrics, a stroke is their first major sickle cell event,” she said.

 When tissues are starved of oxygen, something as simple as a change in the weather can trigger excruciating pain – called a sickle cell crisis – lasting from hours to days or even weeks. That often sends sickle cell sufferers to emergency rooms for treatment, including pain killers and blood transfusions.

 Sickled red blood cells also die prematurely: The distorted cells die within 10 to 20 days, compared to normal red blood cells that typically last 100 to 120 days. That leads to a shortage of red blood cells, a type of anemia. Here again, transfusions are crucial.

 Glinda is 64. “When I was born, life expectancy for a sickle cell patient was 18 years. Now it’s 40 to 60 years, thanks to medications and research,” she said. However, over time, patients may be subject to persistent infections, and damage to kidneys, heart, lungs and other organs.

 SCD affects more than 100,000 people in the United States. Eight out of 10 of them are of African descent; the rest are Hispanic or trace their ancestry to south Asia (such as India), southern Europe (Greece and Italy) or the Middle East (such as Saudi Arabia and Lebanon).

 SCD testing is part of the routine blood tests for newborns in the United States. Additionally, the Red Cross provides sickle cell trait testing for all blood donors who identify themselves as Black or African American. Those with the “trait” inherited a sickle cell gene from one parent; those who got a sickle cell gene from both parents are born with the disease.

Since the best blood match for a patient receiving ongoing transfusions comes from donors of the same genetic background, the Red Cross is urging people of all ethnicities to give blood and help increase the number of diverse donors, so we can find the best match for all patients.

Watch this video that documents Glinda’s ongoing struggle with sickle cell disease.

In honor of Juneteenth, learn more about SCD and please make an appointment to donate blood at RedCrossBlood.org/SickleCell.

Posted by Ryan Lang, American Red Cross board member and volunteer

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